Radiobiology for the Radiologist 8/e 2019
目次
SECTION I For Students of Diagnostic Radiology, Nuclear Medicine, and
Radiation Oncology 1
1 Physics and Chemistry of Radiation Absorption 2
2 Molecular Mechanisms of DNA and Chromosome Damage and Repair 11
3 Cell Survival Curves 35
4 Radiosensitivity and Cell Age in the Mitotic Cycle 54
5 Fractionated Radiation and the Dose-Rate Effect 67
6 Oxygen Effect and Reoxygenation 82
7 Linear Energy Transfer and Relative Biologic Effectiveness 101
8 Acute Radiation Syndrome 111
9 Medical Countermeasures to Radiation Exposure 126
10 Radiation Carcinogenesis 135
11 Heritable Effects of Radiation 162
12 Effects of Radiation on the Embryo and Fetus 177
13 Radiation Cataractogenesis 191
14 Radiologic Terrorism 197
15 Doses and Risks in Diagnostic Radiology, Interventional Radiology and
Cardiology, and Nuclear Medicine 206
16 Radiation Protection 237
SECTION II For Students of Radiation Oncology 257
17 Molecular Techniques in Radiobiology 258
18 Cancer Biology 295
19 Dose–Response Relationships for Model Normal Tissues 327
20 Clinical Response of Normal Tissues 351
21 Model Tumor Systems 380
22 Cell, Tissue, and Tumor Kinetics 398
23 Time, Dose, and Fractionation in Radiotherapy 417
24 Retreatment after Radiotherapy: The Possibilities and the Perils 437
25 Alternative Radiation Modalities 444
26 The Biology and Exploitation of Tumor Hypoxia 458
27 Chemotherapeutic Agents from the Perspective of the Radiation Biologist 475
28 Hyperthermia 516
Glossary 534
Index 564
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