內容簡介

Fields Virology is the authoritative reference book for virology, providing definitive coverage of all aspects of virology, including thorough coverage of virus biology as well as replication and medical aspects of specific virus families.  With the regular outbreaks of influenza, noroviruses as well as other emerging and re-emerging viruses it is essential to have the most up-to-date information available.

With this Sixth Edition, all chapters have been completely updated, an important new emphasis has been placed on virus discovery and emerging viruses. Viruses associated with cancer, including the new human polyomaviruses, are highlighted in this Sixth Edition and new chapters have been added on circoviruses and mimiviruses. 

While the main focus of this edition continues to be on viruses, information on prions and the infectious spongiform encephalopathies are also included.

FEATURES
• 2-volume set
• Full color throughout with over 1,000 illustrations in total and most chapters provide key figures for use as lecture slides
• Online companion website with fully searchable text, all references linked to PubMed and additional material not found in the print for access to content anytime
• New coverage of emerging and viruses, including those causing influenza and HIV
• Updated coverage of viruses and cancer
• Coverage includes virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune responses and vaccines, antiviral therapeutics, virus evolution and immunization
• Thorough coverage of all viruses of medical importance, including both basic science and clinical features
• New chapters on circoviruses and mimiviruses and a new section on Chikungunya virus have been added
• Important advances in antivirals, including new HCV protease inhibitors and HIV integrase inhibitors

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作者簡介

◎David M. Knipe PhD

◎Peter M. Howley MD

◎Diane E. Griffin MD, PhD

◎Robert A. Lamb PhD, ScD

◎Malcolm A. Martin MD

◎Bernard Roizman ScD

◎Stephen E. Straus MD

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目次

SECTION I: GENERAL VIROLOGY

1

History of Virology

Lynn W. Enquist and Vincent R. Racaniello

2

Principles of Virology

Richard C. Condit

3

Principles of Virus Structure

Stephen C. Harrison

4

Virus Entry and Uncoating

Ari Helenius

5

Virus Replication Strategies

Sean Whelan

6

Virus Assembly

Eric Hunter

7

Viruses, Cell Transformation, and Cancer

Daniel DiMaio and Hung Fan

8

Innate Responses to Viral Infections

Akiko Iwasaki and Ruslan Medzhitov

9

Adaptive Immune Response to Viral Infections

Thomas J. Braciale, Young S. Hahn, and Dennis R. Burton

10

Pathogenesis of Viral Infections

Mark T. Heise and Herbert W. Virgin

11

Virus Evolution

Edward C. Holmes

12

Epidemiology

13

Antiviral Agents

Donald M. Coen and Douglas D. Richman

14

Immunization Against Viral Diseases

Barney S. Graham, James E. Crowe, Jr., and Julie E. Ledgerwood

15

Diagnostic Virology and Virus Discovery

Gregory A. Storch and David Wang

SECTION II: SPECIFIC VIRUS FAMILIES

Picornaviridae

16

Picornaviridae: The Viruses and Their Replication

Vincent R. Racaniello

17

Enteroviruses

Authors to come

18

Rhinoviruses

James E. Gern and Ann C. Palmenberg

19

Hepatitis A Virus

F. Blaine Hollinger and Annette Martin

Calciviridae

20

Caliciviridae: The Noroviruses

Kim Y. Green

Astroviridae

21

Astroviruses

Ernesto Méndez and Carlos F. Arias

Togaviridae

22

Togaviridae

Richard J. Kuhn

23

Alphaviruses

Diane E. Griffin

24

Rubella Virus

Tom Hobman

Flaviviridae

25

Flaviviridae

Brett D. Lindenbach, Catherine L. Murray, Heinz-Jürgen Thiel, and Charles M. Rice

26

Flaviviruses

Theodore C. Pierson and Michael S. Diamond

27

Hepatitis C Virus

Stuart C. Ray, Justin R. Bailey, and David L. Thomas

Coronoviridae

28

Coronaviridae

Paul S. Masters and Stanley Perlman

Arteriviridae

29

Arteriviruses

Eric J. Snijder and Marjolein Kikkert

Order Mononegavirales

30

Mononegavirales

Robert A. Lamb

Rhabdoviridae

31

Rhabdoviridae

Douglas S. Lyles, Ivan V. Kuzmin, and Charles E. Rupprecht

Filoviridae

32

Filoviridae: Marburg and Ebola Viruses

Heinz Feldmann, Anthony Sanchez, and Thomas W. Geisbert

Paramyxoviridae

33

Paramyxoviridae

Robert A. Lamb and Griffith D. Parks

34

Parainfluenza Viruses

Ruth A. Karron and Peter L. Collins

35

Mumps Virus

Steven Rubin, Christian Sauder, and Kathryn Carbone

36

Measles Virus

Diane E. Griffin

37

Henipaviruses

Lin-Fa Wang, John S. Mackenzie, and Christopher C. Broder 

38

Respiratory Syncytial Virus and Metapneumovirus

Peter L. Collins and Ruth A. Karron

Bornaviridae

39

Bornaviridae

Christiane Herden, Thomas Briese, W. Ian Lipkin, and Jürgen A. Richt

Orthomyxoviridae

40

Orthomyxoviridae

Megan L. Shaw and Peter Palese

41

Orthomyxoviruses

Peter F. Wright, Gabriele Neumann, and Yoshihiro Kawaoka

Bunyaviridae

42

Bunyaviridae

Richard M. Elliott and Connie S. Schmaljohn

Arenaviridae

43

Arenaviridae

Authors to come

Reoviridae

44

Orthoreoviruses

Terence S. Dermody, John Parker, and Barbara Sherry

45

Rotaviruses

Mary K. Estes and Harry B. Greenberg

46

Orbiviruses

Polly Roy

Retroviridae

47

Retroviridae

Stephen P. Goff

48

Human T Cell Leukemia Virus Types 1 and 2

Masahiro Fujii and Masao Matsuoka

49

Human Immunodeficiency Viruses: Replication

50

HIV-1: Pathogenesis, Clinical Manifestations, and Treatment

Daniel R. Kuritzkes and Richard A. Koup

51

Nonhuman Lentiviruses

David T. Evans, John H. Elder, and Ronald C. Desrosiers

52

Foamy Viruses

Axel Rethwilm and Dirk Lindemann

Polyomaviridae

53

Polyomaviruses

James A. DeCaprio, Michael J. Imperiale, Eugene O. Major

Papillomaviridae

54

Papillomaviruses

Peter M. Howley, John C. Schiller, and Douglas R. Lowy

Adenoviridae

55

Adenoviridae

Arnold J. Berk

56

Adenoviruses

William S. M. Wold and Michael G. Ison

Parvoviridae

57

Parvoviridae

Kenneth I. Berns and Colin R. Parrish

Circoviridae

58

Circoviridae

Xiang-Jin Meng

Herpesviridae

59

Herpesviridae

Philip E. Pellett and Bernard Roizman

60

Herpes Simplex Viruses

Bernard Roizman, David M. Knipe, and Richard J. Whitley

61

Epstein-Barr Virus/Replication and Epstein-Barr Virus

Richard Longnecker, Elliott Kieff, and Jeffrey I. Cohen

62

Cytomegaloviruses

Edward S. Mocarski, Jr, Thomas Shenk, Paul Griffiths, and Robert F. Pass

63

Varicella-Zoster Virus

Ann M. Arvin and Don Gilden

Ann M. Arvin and Don Gilden

64

Human Herpesvirus 6 and 7

Koichi Yamanishi, Yasuko Mori, and Philip E. Pellett

65

Kaposi’s Sarcoma–Associated Herpesvirus

Blossom Damania and Ethel Cesarman

Poxviridae

66

Poxviridae

Bernard Moss

67

Poxviruses

Inger K. Damon

Hepadnaviridae

68

Hepadnaviruses

Cristoph Seeger, Fabien Zoulim, and William S. Mason

Genus Deltavirus

69

Hepatitis D

John M. Taylor, Robert H. Purcell, and Patrizia Farci

Hepeviridae

70

Hepatitis E Virus

Suzanne U. Emerson and Robert H. Purcell

Other Virus Groups

71

Mimi Viruses

Philippe Colson and Didier Raoult

72

Plant Viruses

W. Allen Miller and Steven A. Whitham

73

Insect Viruses

Paul D. Friesen

74

Viruses and Prions of Yeasts, Fungi, and Unicellular Organisms

Reed B. Wickner

75

Bacteriophages

Roger W. Hendrix

Unclassified Agents

76

Prions

Stanley B. Prusiner

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