Molecular Principles of Fungal Pathogenesis 2006
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$ 5,510
售價
$ 5,235
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內容簡介
A compendium of research in the field of medical mycology. - Measures the impact of genome projects, genetics, and molecular biology on the understanding of a diverse group of pathogenic fungi and explores the potential impact of vaccines and new therapeutic approaches to treatment. - Provides a broad overview of pathogenic fungi, including ascomycetes, basidiomycetes, zygomycetes, and both rare and common infections. - Focuses on immunological aspects of infection involving innate, humoral, and cell-mediated immunity. - Features comprehensive coverage of everything from general principles to specific pathogens and vaccine development. - Offers an in-depth analysis of the host-pathogen relationship, and comtemplates future directions. - Serves as a valuable resource for students, fellows, instructors, researchers, specialists, clinicians, and anyone interested in the general field of microbial pathogenesis.
目次
Fungal molecular pathogenesis : what can it do and why do we need it? / John R. Perfect and Arturo Casadevall
Sex, MAT, and the evolution of fungal virulence / James A. Fraser and Joseph Heitman
Postgenomic strategies for genetic analysis : insight from Saccharomyces cerevisiae and Candida albicans / Clarissa J. Nobile and Aaron P. Mitchell
Candida albicans hypha formation and virulence / Paula Sundstrom
The conversion from classical studies in fungal pathogenesis to the molecular era / Kyung J. Kwon-Chung and Brian L. Wickes
Mating and parasexual genetics in Candida albicans / Mathew Miller and Alexander Johnson
The mating-type locus and mating of Candida albicans and Candida glabrata / David R. Soll
Evolution of human pathogenic fungi : phylogenies and species / John W. Taylor
Establishment of cell identity in pathogenic fungi / Christina M. Hull
Signal transduction in the interactions of fungal pathogens and mammalian hosts / Malcolm Whiteway and Catherine Bachewich
Function and regulation of adhesin gene families in Saccharomyces cerevisiae, Candida albicans, and Candida glabrata / Irene Castaño, Alejandro de las Peñas, and Brendan P. Cormack. Fungal biofilms : agents of disease and drug resistance / Gordon Ramage, Mahmoud A. Ghannoum, and José L. López-Ribot
Molecular basis of fungal adherence to endothelial and epithelial cells / Scott G. Filler, Donald C. Sheppard, and John E. Edwards, Jr
Molecular principles of antifungal drug resistance / Dominique Sanglard and Theodore C. White
Heterologous hosts and the evolution and study of fungal pathogenesis / Eleftherios Mylonakis, Stephen B. Calderwood, and Frederick M. Ausubel
Amoeba and slime mold: hosts of virulence evolution / Arturo Casadevall
Aspergillus nidulans : a model for elucidation of Aspergillus fumigatus secondary metabolism / Nancy Keller
Saccharomyces cerevisiae : an emerging and model pathogenic fungus / John H. McCusker
Fungal-bacterial interactions / Deborah A. Hogan and Roberto Kolter
Amphibian chytridiomycosis as an emerging infectious disease of wildlife : what can we learn from the earliest diverging fungi? / Timothy Y. James and Rytas Vilgalys
Cryptococcus neoformans : a sugar-coated killer / John R. Perfect
Toward a molecular understanding of Candida albicans virulence / Frank C. Odds, Neil A.R. Gow, and Alistair J.P. Brown
Molecular determinants of Histoplasma capsulatum pathogenesis / Jon P. Woods
Molecular determinants of virulence in Aspergillus fumigatus / Judith C. Rhodes and Axel A. Brakhage
Pathogenesis of pneumocystis / A. George Smulian and Melanie T. Cushion. Virulence mechanisms of coccidioides / Garry T. Cole [and others]
Blastomyces dermatitidis cell surface determinants and their application in vaccine development / Bruce Klein
Virulence factors in black molds with emphasis on melanin, chitin, and Wangiella as a molecularly tractable model / Paul J. Szaniszlo
Zygomycetes as agents of infectious disease in humans / Ashraf S. Ibrahim and Brad Spellberg
Signaling pathways in the dimorphic human fungal pathogen Penicillium marneffei / Alex Andrianopoulos and Sophie Zuber
Innate humoral immunity to fungi / Thomas R. Kozel
Innate and acquired cellular immunity to fungi / Luigina Romani
Acquired antibody-mediated immunity to fungi / Liise-anne Pirofski and Arturo Casadevall
Site-specific mucosal immunity to fungi : lessons learned from Candida albicans applied to other fungi / Paul L. Fidel, Jr. and Beatriz Finkel-Jimenez
Intracellular pathogenesis of Histoplasma capsulatum / Simon L. Newman
Interactions of immune cells with the facultative intracellular pathogen Cryptococcus neoformans / Lauren E. Yauch and Stuart M. Levitz. Fungal interactions with leukocytes / Mairi C. Noverr [and others]
Fungal vaccine development / Joshua D. Nosanchuk and George S. Deepe Jr
Molecular immunopathogenesis of innate host defense against chronic disseminated (hepatosplenic) candidiasis / Thomas J. Walsh [and others]
Studying fungal virulence using genomics / Michael C. Lorenz
Future of functional genomics of Histoplasma capsulatum / Anita Sil and Lena Hwang
Functional genomic approaches to fungal pathogenesis, drug target validation, and antifungal drug discovery / Ainslie B. Parsons, Howard Bussey, and Charles Boone
Genetic and proteomic analysis of fungal virulence / Jennifer K. Lodge and Michael C. Lorenz
Genomic perspectives on the fungal kingdom / Jason E. Stajich and Fred S. Dietrich
ISBN-13碼 :
9781555813680
ISBN-10碼 :
1555813682
出版日期 :
2006
書系代碼 :
06598
作者 :
Joseph Heitman．Scott G Filler．John E Edwards．Aaron P Mitchell
開數 :
菊8開
頁數 :
684
裝訂 :
精裝
印刷 :
彩色
定價 :
5510
