Designed for students in biology, biochemistry, and biomedicine, Introduction to Protein Science, Second Edition, provides a wide-ranging introduction to the contemporary study of proteins in health and disease. The text describes basic principles of protein structure and methods for studying them, illustrates the wide variety of functions that proteins have, and shows how their structures and functions are closely linked.

 

Introduction to Protein Science, Second Edition, relates the study of proteins to the context of modern high-throughput data streams of genomics and proteomics. It also provides a balanced treatment of the relationship between computational and experimental methods. The text is enhanced by marginal notes, exercises, problems, and "weblems" that develop students' database and computational server skills. An updated and expanded Companion Website offers resources for students and instructors.

 

1. Introduction ; 

2. Protein structure ; 

3. Protein structure determination ; 

4. Bioinformatics of protein sequence and structure ; 

5. Proteins as catalysts: enzyme structure, kinetics, and mechanism ; 

6. Proteins with partners ; 

7. Evolution of protein structure and function ; 

8. Protein folding and design ; 

9. Proteomics and systems biology