In this updated edition of Basic Immunology, the authors continue to deliver a clear, modern introduction to immunology, making this the obvious choice for today's busy students. Their experience as teachers, course directors, and lecturers helps them to distill the core information required to understand this complex field. Through the use of high-quality illustrations, relevant clinical cases, and concise, focused text, it's a perfectly accessible introduction to the workings of the human immune system, with an emphasis on clinical relevance.

 

• Concise, clinically focused content is logically organized by mechanism for efficient mastery of the material.

• Features an appendix of clinical cases and CD molecules.

• Includes numerous full-color illustrations, useful tables, and chapter outlines.

• Focus questions within each chapter are ideal for self-assessment and review.

• Key points bolded throughout the text make it easy to locate important information.

• Presents information in a format and style that maximizes usefulness to students and teachers studying medicine, allied health fields, and biology.

• Fully updated content equips you with the latest relevant advances in immunology.

• Revised and updated artwork enhances your visual learning of important principles and reduces the excessive factual details found in larger textbooks.

• Twelve brand-new animations available on Student Consult help further explain complex concepts.

• Student Consult eBook version included with purchase. This enhanced eBook experience gives you access to the text, figures, images, glossary of immunology terms, self-assessment questions, and references on a variety of devices.

1 INTRODUCTION TO THE IMMUNE SYSTEM,

 

Nomenclature, General Properties, and Components

 

2 INNATE IMMUNITY,

 

The Early Defense Against Infections

 

3 ANTIGEN CAPTURE AND PRESENTATION TO LYMPHOCYTES,

 

What Lymphocytes See

 

4 ANTIGEN RECOGNITION IN THE ADAPTIVE IMMUNE SYSTEM,

 

Structure of Lymphocyte Antigen Receptors and Development of Immune Repertoires

 

5 T CELL-MEDIATED IMMUNITY,

 

Activation of T Lymphocytes by Cell-Associated Antigens

 

6 EFFECTOR MECHANISMS OF T CELL-MEDIATED IMMUNITY,

 

Functions of T Cells in Host Defense

 

7 HUMORAL IMMUNE RESPONSES,

 

Activation of B Lymphocytes and Production of Antibodies

 

8 EFFECTOR MECHANISMS OF HUMORAL IMMUNITY,

 

Elimination of Extracellular Microbes and Toxins

 

9 IMMUNOLOGICAL TOLERANCE AND AUTOIMMUNITY,

 

Self-Nonself Discrimination in the Immune System and Its Failure

 

10 IMMUNE RESPONSES AGAINST TUMORS AND TRANSPLANTS,

 

Immunity to Noninfectious Transformed and Foreign Cells

 

11 HYPERSENSITIVITY,

 

Disorders Caused by Immune Responses

 

12 CONGENITAL AND ACQUIRED IMMUNODEFICIENCIES,

 

Diseases Caused by Defective Immunity

 

SELECTED READINGS,

 

APPENDIX I,

 

Glossary

 

APPENDIX II,

 

Cytokines

 

APPENDIX III,

 

Principal Features of Selected CD Molecules

 

APPENDIX IV,

 

Clinical Cases

 

INDEX,