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內容簡介

Immunobiology is the premier text for immunology at the advanced undergraduate, graduate and medical school levels. Beginning students appreciate the book’s clear writing and informative illustrations, while advanced students and working immunologists value its comprehensive scope. Every chapter is reviewed with experts to ensure accuracy, authority, currency and depth. The Tenth Edition is supported by InQuizitive, Norton’s award-winning, easy-to-use adaptive learning tool that helps students learn immunological terms and apply them conceptually.

作者簡介

Kenneth Murphy is the Eugene Opie First Centennial Professor of Pathology and Immunology at Washington University School of Medicine in St. Louis. He received his MD/PhD degree from The Johns Hopkins University School of Medicine. He is a member of the National Academy of Sciences.

Casey Weaver is the Wyatt and Susan Haskell Professor of Medical Excellence in the Department of Pathology at the University of Alabama at Birmingham School of Medicine. He received his MD degree from the University of Florida. His residency and post-doctoral training were completed at Barnes Hospital and Washington University in St. Louis.

Leslie Berg is the chair of the Department of Immunology and Microbiology at University of Colorado Medical School. She served as president of the American Association of Immunologists in 2011–2012 and has received numerous academic awards and honors, including the 2020 American Association of Immunologists Distinguished Fellow Award. She received her PhD at University of California at Berkeley and trained as a postdoctoral fellow at Stanford University School of Medicine.

目次

Part I: An Introduction to Immunobiology and Innate Immunity
Chapter 1: Basic Concepts in Immunology
Chapter 2: Innate Immunity: The First Lines of Defense
Chapter 3: Cellular Mechanisms of Innate Immunity 
 
Part II: The Recognition of Antigen
Chapter 4: Antigen Recognition by B-cell and T-cell Receptors
Chapter 5: The Generation of Lymphocyte Antigen Receptors
Chapter 6: Antigen Presentation to T Lymphocytes
 
Part III: The Development of Mature Lymphocyte Receptor Repertoires
Chapter 7: Lymphocyte Receptor Signaling
Chapter 8: The Development of B and T Lymphocytes
 
Part IV: The Adaptive Immune Response
Chapter 9: T Cell–Mediated Immunity
Chapter 10: The Humoral Immune Response
Chapter 11: Integrated Dynamics of Innate and Adaptive Immunity
Chapter 12: The Barrier Immune System
 
Part V: The Immune System in Health and Disease
Chapter 13: Failures of Host Defense Mechanisms
Chapter 14: Allergic Diseases and Hypersensitvity Reactions
Chapter 15: Autoimmunity and Transplantation
Chapter 16: Manipulation of the Immune Response
 
Appendix I: The Immunologist’s Toolbox