Unifying Microbial Mechanisms Shared Strategies of Pathogenesis

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Unifying Microbial Mechanisms Shared Strategies of Pathogenesis

內容簡介

Microbial pathogenesis is the study of the mechanisms by which microbes (bacteria, viruses, protozoa, and multicellular parasites) cause infectious disease and make their hosts (humans) ill. Bacterial infections we thought were easily treatable are again a huge cause for concern with the well-publicized rise of antibiotic resistance. There are very few effective antiviral drugs and we live with the threat of epidemics such as bird flu and the outbreaks of viruses such the recent (and ongoing) Ebola crisis. Parasitic diseases such as malaria continue to pose a heavy burden in the developing world and with climate change could spread into the developed world. There is therefore an urgent need to understand microbial mechanisms, with research programmes and university courses dedicated to the subject.


作者簡介

Mike Cole is an experienced instructor at Georgetown University where he is professor of microbiology and immunology and teaches microbial pathogenesis, immunology, and bacteriology. His research interests are into the regulation of commensal and pathogenic bacteria at the mucosal surface by the secretory immune response and the ontogeny of the secretory immune system. He regularly attends the ASM education conference and is the author of half the bacterial cases in Case Studies in Infectious Disease.


目次

Chapter 1: Introduction to Pathogenesis
Chapter 2: Normal Microbiotas of the Human Body
Chapter 3: Biofilms
Chapter 4: Adhesion to Host Surfaces
Chapter 5: Facilitated Cell Entry
Chapter 6: Exotoxins and Endotoxins
Chapter 7: Extracellular Degradative Enzymes
Chapter 8: Evasion of the Human Innate Immune System
Chapter 9: Evasion of the Human Adaptive Immune System 263IntroductionAntigen presentationLinking sensing of MAMPs by pattern-recognitionreceptors with antigen processing
Chapter 10: Persistent and Latent Infections 295IntroductionPersistent bacterial infectionsIntroduction
Index

ISBN-13碼 : 9780815345404
出版日期 : 2019
書系代碼 : 26594
作者 : Michael F. Cole
開數 : 16開
頁數 : 345
裝訂 : 平裝
印刷 : 彩色
定價 : 1200

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