Oncogenomics: Molecular Approaches to Cancer 2004

定價 $ 1,550

售價 $ 1,473

數量:

Oncogenomics: Molecular Approaches to Cancer 2004-需求單

內容簡介

This book aims to assemble the only available rigorous, yet broadly accessible introduction to this new and exciting field. Oncogenomics: Molecular Approaches to Cancer is approachable by basic scientists, practitioners, and other health professionals required to familiarize themselves with the tremendous impact of genomics and proteomics on cancer research. Clearly written chapters offer reviews of state of the art topics such as molecular classification, early detection, SNPs in cancer, data mining, tissue microarrays, protein and antibody arrays, and drug targets.

PART I: INTRODUCTION.

01. At the Precarious Cusp of Oncogenomics (C. Brenner).

PART II: MOLECULAR PROFILING IN CANCER: DNA, RNA AND PROTEIN.

02.Genome-Wide Searches for Mutations in Human Cancer (M. Stratton, et al.).

03. Molecular Cytogenetics: Increasing Resolution Using Array-Based CGH (A. Kallioniemi).

04. SNPs and Functional Polymorphisms in Cancer (P. Bonnen & D. Nelson).

05. Expression Profiling of Breast Cancer: From Molecular Protraits to Clinical Utility (T. Sorlie, et al.).

06. Classifying Hereditary Cancers and Phenocopies of Herditary Cancers Using Expression Arrays (M. Daly, et al.).

07. Linking Drugs and_ Genes: Pharmacogenomics, Pharmacoproteomics, Bioinformatics, and the NCI-60 (J. Weinstein).

08. Tissue Microanalysis: Profiling Cancer Stages (M. Tangrea & M. Emmert-Buck).

09. Proteomics in Bladder Cancer (J. Celis, et al.).

PART III: MODEL SYSTEMS.

10. Chemical and Genetic Methods to Validate Targets in Non-Mammalian Organisms (T. Maiolatesi & C. Brenner).

11. Mouse Models of Cancer (D. Thompson, et al.).

12. Genome-Wide Modifier Screens: How the Genetics of Cancer Penetrance May Shape the Future of Prevention and Treatment (L. Siracusa, et al.).

PART IV: MOLECULARLY TARGETED DRUGS AND IMAGING.

13. Protein Kinases as Targets in Cancer Therapy: Validated and Emerging Approaches (P. Nghiem, et al.).

14. Ras Superfamily-Directed Compounds (G. Prendergast).

15. Clinomics: Post-Genomic Cancer Care (D. Von Hoff, et al.).

PART V: CONCLUSION.

16. Oncogenomics Tomorrow: Prevention, Early Detection and Treatment.

ISBN-13碼 : 9780471225928

出版日期 : 2004

ISBN-10碼 : 0471225924

書系代碼 : 30053

作者 : Charles Brenner．David Duggan

開數 : 16開

頁數 : 382

裝訂 : 精裝

定價 : NT$1,550.00