內容簡介
Medical Biochemistry at a Glance provides a concise and accessible introduction to this complex subject and a revision aid for medical students. Following the familiar, easy–to–use at a Glance format, each topic is presented as a double–page spread with key facts accompanied by clear tables and diagrams encapsulating all the students need to know. This new edition of Medical Biochemistry at a Glance : Has been completely re–organised, revised and updated Is written by the author of the hugely successful Metabolism at a Glance Contains a second colour throughout to enhance the visual appeal, making the subject even easier to understand Presents line drawings and biochemical pathways on the left page and concise explanations of the right, providing a user–friendly overview of medical biochemistry Condenses medical biochemistry into 60 digestible double–page spreads Medical Biochemistry at a Glance will appeal to medical students in the early years of their course, and those revising for final exams. The book is also suitable for biological science and biochemistry students.
作者簡介
Dr Jack Salway– School of Biological Sciences, University of Surrey.
目次
1. Acids, bases and hydrogen ions (protons)
2. Understanding pH
3. Production and removal of protons into and from the blood
4. Metabolic acidosis and metabolic alkalosis
5. Respiratory acidosis and respiratory alkalosis
6. Amino acids and the primary structure of proteins
7. Secondary structure of proteins
8. Tertiary and quaternary structures;collagen
9. Enzymes: nomenclature, kinetics and inhibitors
10. Regulation of enzyme activity
11. Carbohydrates
12. Absorption of carbohydrates and metabolism of galactose
13. Oxidation/reduction reactions, coenzyme and prosthetic groups
14. Anaerobic production of ATP by substrate-level phosphorylation, phosphocreatine, adenylate kinase
15. Aerobic production of ATP
16. Biosynthesis of ATP by oxidative phosphorylation I
17 The biosynthesis of ATP by oxidative phosphorylation II
18. What happens when protons or electrons leak from the respiratory chain?
19. Free radicals, reactive oxygen species and oxidative damage
20. Aerobic oxidation of glucose to provide energy as ATP
21. Anaerobic oxidation of glucose by glycolysis to form ATP and lactate
22. Anaerobic glycolysis in red blood cell, 2,3 BPG and the Bohr effect
23. The fate of glucose in liver: glycogenesis and lipogenesis
24. Fructose metabolism
25. Glucose homeostasis
26. Glucose-stimulated secretion of insulin from the beta-cell
27. Regulation of glycogen metabolism
28. Glycogen breakdown (glycogenolysis and glycogen storage diseases)
29. Insulin signal transduction and Diabetes mellitus
30. Regulation of glycolysis and Krebs cycle
31. Oxidation of fatty acids to produce ATP in muscle and ketone bodies in liver
32. Regulation of lipolysis, beta-oxidation, ketogenesis and gluconeogenesis
33. Diabetes mellitus
34. Alcohol metabolism: hypoglycemia, hyperlactataemia and steatosis
35. Structure of lipids
36. Phospholipids I
37. Phospholipids II: micelles, liposomes, lipoproteins and membranes
38. Metabolism of carbohydrate and fat to cholesterol
39. VLDL and LDL metabolism ("forward" cholesterol transport)
40. VLDL and LDL metabolism (endogenous triacylglycerol transport)
41. HDL metabolism ("reverse" cholesterol transport)
42. Digestion and disposal of dietary triacylglycerol and cholesterol by chylomicrons
43. Steroid hormones: aldosterone, cortisol, androgens and oestrogens
44. Urea cycle and overview of amino acid catabolism
45. Nonessential and essential amino acids
46. Amino acid metabolism: to energy as ATP; to glucose and ketone bodies
47. Amino acid disorders: maple syrup urine disease, homocystinuria, alkaptonuria and albinism
48. Phenylalanine and tyrosine metabolism in health and disease
49. The products of tryptophan and histidine metabolism
50. Pyrimidine metabolism
51. Purine metabolism
52. Haem, bilirubin and porphyries
53. Fat-soluble vitamins I
54. Fat-soluble vitamins II
55. Water-soluble vitamins 1 thiamin. riboflavin, niacin and pantothenate
56. Water-soluble vitamins 2 pyridoxal phosphate
57. Water-soluble vitamins 3 folate and vitamin B12
58. Water-soluble vitamins 4 biotin and vitamin C
