Biochemistry: A Short Course 4/e 2019
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內容簡介
Derived from the classic text originated by Lubert Stryer and continued by John Tymoczko and Jeremy Berg, Biochemistry: A Short Course focuses on the major topics taught in a one-semester biochemistry course. With its brief chapters and relevant examples, this thoroughly updated new edition helps students see the connections between the biochemistry they are studying and their own lives.
Now with SaplingPlus, Learning objectives and active learning questions. SaplingPlus is an online solution that combines an e-book of the text, Berg's powerful multimedia resources, and Sapling’s robust biochemistry problem library.
．Thoroughly updated text and figures based on latest research and discoveries in biochemistry and related fields.
．‘Biochemistry in Focus’ appendix added to the EOC material in most every chapter—designed to explore the application of chapter content to an engaging example, such as disease.
．New ‘Problem-Solving Strategies’ appendix added to the EOC material in most chapters. Designed to unpack one or two problems related to the chapter content. This process will help students understand how to solve complex multipart problems in biochemistry.
．New ‘Industry Insights’ and ‘Clinical and Biological Insights’ have been updated to address current research and technologies.
．Refreshed design for 4e that includes newly styled icons and color scheme. Also includes some new chapter opening photos.
作者簡介
John L. Tymoczko was Towsley Professor of Biology Emeritus at Carleton College, where he taught from 1976 until his death in 2019. He taught a variety of courses, including Biochemistry, Biochemistry Laboratory, Oncogenes and the Molecular Biology of Cancer, and Exercise Biochemistry, and cotaught an introductory course, Energy Flow in Biological Systems. Professor Tymoczko received his B.A. from the University of Chicago in 1970 and his PhD in Biochemistry from the University of Chicago with Shutsung Liao at the Ben May Institute for Cancer Research. He then had a postdoctoral position with Hewson Swift of the Department of Biology at the University of Chicago. The focus of his research was on steroid receptors, ribonucleoprotein particles, and proteolytic processing enzymes.
Jeremy M. Berg received his B.S. and M.S. degrees in Chemistry from Stanford University (where he did research with Keith Hodgson and Lubert Stryer) and his PhD in Chemistry from Harvard with Richard Holm. He then completed a postdoctoral fellowship with Carl Pabo in Biophysics at Johns Hopkins University School of Medicine. He was an Assistant Professor in the Department of Chemistry at Johns Hopkins from 1986 to 1990. He then moved to Johns Hopkins University School of Medicine as Professor and Director of the Department of Biophysics and Biophysical Chemistry, where he remained until 2003. He then became Director of the National Institute of General Medical Sciences at the National Institutes of Health. In 2011, he moved to the University of Pittsburgh, where he is now Professor of Computational and Systems Biology and Pittsburgh Foundation Chair and Director of the Institute for Personalized Medicine. He served as President of the American Society for Biochemistry and Molecular Biology from 2011 to 2013 and as Editor-in-Chief for Science magazine and the Science family of journals from 2016 to 2019. Dr. Berg has received numerous awards for his research, teaching, and public service. He is an elected member of the National Academy of Medicine and the American Academy of Arts and Sciences. He is coauthor, with Stephen J. Lippard, of the textbook Principles of Bioinorganic Chemistry. He greatly enjoys sharing his life with his wife, three grown children, and grandchildren.
Gregory J. Gatto, Jr., received his A.B. degree in Chemistry from Princeton University, where he worked with Martin F. Semmelhack and was awarded the Everett S. Wallis Prize in Organic Chemistry. In 2003, he received his MD and PhD degrees from the Johns Hopkins University School of Medicine, where he studied the structural biology of peroxisomal targeting signal recognition with Dr. Berg and received the Michael A. Shanoff Young Investigator Research Award. He completed a postdoctoral fellowship in 2006 with Christopher T. Walsh at Harvard Medical School, where he studied the biosynthesis of the macrolide immunosuppressants. Dr. Gatto is currently a Scientific Director in the Novel Human Genetics Research Unit at GlaxoSmithKline. While he enjoys losing at board games, attempting but not completing crossword puzzles, and watching baseball games at every available opportunity, he treasures most the time he spends with his wife Megan and sons Timothy and Mark.
Lubert Stryer is Winzer Professor of Cell Biology, Emeritus, in the School of Medicine and Professor of Neurobiology, Emeritus, at Stanford University, where he has been on the faculty since 1976. He received his MD from Harvard Medical School. Professor Stryer has received many awards for his research on the interplay of light and life, including the Eli Lilly Award for Fundamental Research in Biological Chemistry, the Distinguished Inventors Award of the Intellectual Property Owners’ Association, and election to the National Academy of Sciences and the American Philosophical Society. He was awarded the National Medal of Science in 2006. The publication of his first edition of Biochemistry in 1975 transformed the teaching of biochemistry.
目次
PART I The Molecular Design of Life
SECTION 1 Biochemistry Helps Us Understand Our World
1. Biochemistry and the Unity of Life
2. Water, Weak Bonds, and the Generation of Order Out of Chaos
SECTION 2 Protein Composition and Structure
3. Amino Acids
4. Protein Three-Dimensional Structure
5. Techniques in Protein Biochemistry
SECTION 3 Basic Concepts and Kinetics of Enzymes
6. Basic Concepts of Enzyme Action
7. Kinetics and Regulation
8. Mechanisms and Inhibitors
9. Hemoglobin, an Allosteric Protein
SECTION 4 Carbohydrates and Lipids
10. Carbohydrates
11. Lipids
SECTION 5 Cell Membranes, Channels, Pumps, and Receptors
12. Membrane Structure and Function
13. Signal-Transduction Pathways
PART II Transducing and Storing Energy
SECTION 6 Basic Concepts and Design of Metabolism
14. Digestion: Turning a Meal into Cellular Biochemicals
15. Metabolism: Basic Concepts and Design
SECTION 7 Glycolysis and Gluconeogenesis
16. Glycolysis
17. Gluconeogenesis
SECTION 8 The Citric Acid Cycle
18. Preparation for the Cycle
19. Harvesting Electrons from the Cycle
SECTION 9 Oxidative Phosphorylation
20. The Electron-Transport Chain
21. The Proton-Motive Force
SECTION 10 The Light Reactions of Photosynthesis and the Calvin Cycle
22. The Light Reactions
23. The Calvin Cycle
SECTION 11 Glycogen Metabolism and the Pentose Phosphate Pathway
24. Glycogen Degradation
25. Glycogen Synthesis
26.The Pentose Phosphate Pathway
SECTION 12 Fatty Acid and Lipid Metabolism
27. Fatty Acid Degradation
28. Fatty Acid Synthesis
29. Lipid Synthesis: Storage Lipids, Phospholipids, and Cholesterol
SECTION 13 The Metabolism of Nitrogen-Containing Molecules
30. Amino Acid Degradation and the Urea Cycle
31. Amino Acid Synthesis
32. Nucleotide Metabolism
PART III Synthesizing the Molecules of Life
SECTION 14 Nucleic Acid Structure and DNA Replication
33. The Structure of Informational Macromolecules: DNA and RNA
34. DNA Replication
35. DNA Repair and Recombination
SECTION 15 RNA Synthesis, Processing, and Regulation
36. RNA Synthesis and Regulation in Bacteria
37. Gene Expression in Eukaryotes
38. RNA Processing in Eukaryotes
SECTION 16 Protein Synthesis and Recombinant DNA Techniques
39. The Genetic Code
40. The Mechanism of Protein Synthesis
41. Recombinant DNA Techniques
ISBN-13碼 :
9781319248086
出版日期 :
2018
版次 :
4
書系代碼 :
04098
作者 :
John Tymoczko．Jeremy M. Berg．Gregory J. Gatto, Jr.．Lubert Stryer
開數 :
菊8開
頁數 :
996
裝訂 :
平裝
印刷 :
彩色
定價 :
2750
